Andheriya Deepti Choursiya Surbhi


Fast-dissolving drug-delivery systems were first developed in the late 1970s as an alternative to tablets, capsules, and syrups for pediatric and geriatric patients who experience difficulties swallowing traditional oral solid dosage forms. In response to this need, a variety of orally disintegrating tablet formats were commercialized. Most orally disintegrating products were formulated to dissolve in less than one minute when exposed to saliva to form a solution that could then be more easily swallowed. Oral thin film a new drug delivery system for the oral delivery of the drugs was developed based on the technology of the transdermal patch. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min when placed in the mouth without drinking of water or chewing. Oral film includes various ingredients for its formulation which includes polymers, active pharmaceutical ingredient, film stabilizing agents, sweeteners, flavors, colors, saliva stimulating agents, preservatives, surfactants etc but the first and far most a very essential ingredient which helps in film formation is a polymer. Dissolvable oral thin films evolved over the past few years from the confection and oral care markets in the form of breath strips and became a novel and widely accepted form by consumers for delivering vitamins and personal care products.

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