A REVIEW ON FAST DISSOLVING DRUG DELIVERY SYSTEM

Andheriya Deepti Choursiya Surbhi

Abstract


Fast-dissolving drug-delivery systems were first developed in the late 1970s as an alternative to tablets, capsules, and syrups for pediatric and geriatric patients who experience difficulties swallowing traditional oral solid dosage forms. In response to this need, a variety of orally disintegrating tablet formats were commercialized. Most orally disintegrating products were formulated to dissolve in less than one minute when exposed to saliva to form a solution that could then be more easily swallowed. Oral thin film a new drug delivery system for the oral delivery of the drugs was developed based on the technology of the transdermal patch. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min when placed in the mouth without drinking of water or chewing. Oral film includes various ingredients for its formulation which includes polymers, active pharmaceutical ingredient, film stabilizing agents, sweeteners, flavors, colors, saliva stimulating agents, preservatives, surfactants etc but the first and far most a very essential ingredient which helps in film formation is a polymer. Dissolvable oral thin films evolved over the past few years from the confection and oral care markets in the form of breath strips and became a novel and widely accepted form by consumers for delivering vitamins and personal care products.

Full Text:

PDF

References


Gavaskar Basani, Kumar Subash Vijaya , Guru Sharan, Rao Y Madhusudan, Overview on fast dissolving films, International Journal of Pharmacy and Pharmaceutical Sciences, 2(3): 2009: 29-33.

Shimoda H and Taniguchi K. Preparation of fast dissolving oral thin film containing dexamethasone: A possible application to antiemetic during cancer chemotherapy. European Journal of Pharmaceutics and Biopharmaceutics 2009; 73: 361-365.

Dixit RP, Puthli SP, Oral strip technology: Overview and future potential. Journal of Controlled Release. 2009; 139: 94–97.

Bhupendra G Prajapati et al ., A Review on Recent patents on Fast Dissolving Drug Delivery System, International Journal of Pharm Tech Research.2009,1(3)

Kulkarni AS, Deokule HA, Mane MS and Ghadge DM. Exploration of different polymers for use in the formulation of oral fast dissolving strips. Journal of Current Pharmaceutical Research 2010; 2(1): 33-35.

Bhyan B, Jangra S, Kaur M and Singh H, Orally fast dissolving films: innovations in formulation and technology. International

Journal of Pharmaceutical Sciences Review and Research 2011; 9(2): 50-57.

Nagar P, Chauhan I, Yasir M. A Review: Insights into Polymers: Film Formers in Mouth Dissolving Films. Drug Invention Today, 2011; 3(12): 280-289.

Bhura N, Sanghvi K, Patel U, Parmar V and Patel D, “A review on fast dissolving film”, IJPRBS, 2012; 1 (3): 66-89.

Swetha Kalyan, Mayank Bansal. Recent Trends in the Development of Oral Dissolving Film. International Journal of Pharm Tech Research 2012; 4(2): 725-33.

Khatoon N, Rao NGR, Reddy BM. Overview on Fast Dissolving Oral Films. Int J Chem Pharmceut. Sci. 2013; 1(1): 63-75.

Narayana PR, Kumar MS, Reddy M, Ravishankar K. Formulation and Evaluation of Fast Dissolving Films of Loratidine by Solvent Casting method. Pharm In nova J. 2013; 2(2): 31-35.

Juluru, NS. Fast Dissolving Oral Films: A Review. Int J Advan Pharm Bio Chem. 2013; 2(1): 108-112.

Satam MN, Bhuruk MD, Pawar YD. Fast Dissolving Oral Thin Films. Int. J Uni Pharm Bio-Sci. 2013; 2(4), 27-39.

Siddeshwar SS, Datta prasad NV, Waghmare GA, Wadghule PB, Varpe PS. Fast Dissolving Oral Films: Easy way of Oral Delivery. Int J Curr Trends Pharmacist. Res. 2014; 2(3): 483-490.

Ravi Kumar K and Mercy Sulochana M. FAST DISSOLVING FILMS: A UNIQUE STRATEGY FOR DRUG DELIVERY .Asian J. Pharm. Res. 2014. , 4(1), 47-55.

Kulkarni AS, Deokule HA, Mane MS and Ghadge DM. Exploration of different polymers for use in the formulation of oral fast dissolving strips. Journal of Current Pharmaceutical Research 2010; 2(1): 33-35.

Arya A, Chandra A, Sharma V and Pathak K. Fast Dissolving Oral Films: An Innovative Drug Delivery System and Dosage Form. Int J of Chem Tech Research 2010; 2(1):576- 583.

Bharkatiya M , Kitawat S, Gaur K , Formulation and Characterization of Fast Dissolving Tablet of Salbutamol Sulphate, American Journal of Pharmacological Sciences 2018, 6(1), 1-6.


Refbacks

  • There are currently no refbacks.